{"product_id":"proton-28-tablets","title":"Proton 28 Tablets","description":"\u003cp data-path-to-node=\"3\"\u003eProton (manufactured by SPIMACO) is an oral delayed-release, gastric antisecretory medication formulated with \u003cb data-path-to-node=\"3\" data-index-in-node=\"110\"\u003ePantoprazole Sodium Sesquihydrate\u003c\/b\u003e, available in two clinical strengths: \u003cb data-path-to-node=\"3\" data-index-in-node=\"182\"\u003e20 mg\u003c\/b\u003e (low\/maintenance dose) and \u003cb data-path-to-node=\"3\" data-index-in-node=\"215\"\u003e40 mg\u003c\/b\u003e (standard therapeutic dose). As a second-generation substituted benzimidazole and irreversible Proton Pump Inhibitor (PPI), it accumulates selectively inside the acidic secretory canaliculi of gastric parietal cells, transforming into an active sulfonamide that binds covalently to the luminal cysteines of the enzyme system. This blocks both basal and meal-stimulated hydrochloric acid output at the final enzymatic step. Formulated with an enteric polymer coating to prevent premature degradation by gastric acid, it delivers mucosal healing, long-term GERD maintenance, and gastroprotection against non-steroidal anti-inflammatory drugs (NSAIDs), packaged in boxes of \u003cb data-path-to-node=\"3\" data-index-in-node=\"907\"\u003e28 gastro-resistant tablets\u003c\/b\u003e.\u003c\/p\u003e\n\u003cp data-path-to-node=\"3\"\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"4\"\u003eKey Benefits\u003c\/h4\u003e\n\u003cul data-path-to-node=\"5\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,0,0\"\u003e\u003cb data-path-to-node=\"5,0,0\" data-index-in-node=\"0\"\u003eDose-Tailored Acid Suppression:\u003c\/b\u003e The 40 mg strength delivers rapid, high-grade suppression to heal erosions and eradicate pathogens, while the 20 mg strength provides balanced, sustained suppression for long-term symptom control and relapse prevention without excessive hypochlorhydria.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,1,0\"\u003e\u003cb data-path-to-node=\"5,1,0\" data-index-in-node=\"0\"\u003eRapid Symptom Relief \u0026amp; High Healing Rates:\u003c\/b\u003e Swiftly relieves retrosternal pyrosis (heartburn), acidic regurgitation, and epigastric pain, driving high endoscopic cicatrization rates in peptic ulcers and reflux esophagitis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,2,0\"\u003e\u003cb data-path-to-node=\"5,2,0\" data-index-in-node=\"0\"\u003eTargeted Prophylaxis Against NSAID Gastropathy:\u003c\/b\u003e The 20 mg dose serves as a protective baseline, preventing gastroduodenal ulcers and mucosal bleeding in chronic NSAID or corticosteroid users.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,3,0\"\u003e\u003cb data-path-to-node=\"5,3,0\" data-index-in-node=\"0\"\u003eEssential Pillar in \u003ci data-path-to-node=\"5,3,0\" data-index-in-node=\"20\"\u003eH. pylori\u003c\/i\u003e Eradication:\u003c\/b\u003e The 40 mg dose (administered twice daily) elevates intragastric pH above 5–6, stabilizing co-prescribed acid-labile antibiotics (clarithromycin and amoxicillin) and promoting bacterial replication to maximize antibiotic-mediated eradication.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"5,4,0\"\u003e\u003cb data-path-to-node=\"5,4,0\" data-index-in-node=\"0\"\u003eFavorable Hepatic Interaction Profile:\u003c\/b\u003e Exhibits significantly lower affinity for cytochrome P450 2C19 compared to omeprazole or esomeprazole, making both strengths the preferred clinical choice when co-prescribed with antiplatelet drugs such as \u003cb data-path-to-node=\"5,4,0\" data-index-in-node=\"245\"\u003eClopidogrel (Plavix)\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"6\"\u003eKey Ingredients \u0026amp; Available Strengths\u003c\/h4\u003e\n\u003cul data-path-to-node=\"7\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,0\"\u003e\u003cb data-path-to-node=\"7,0,0\" data-index-in-node=\"0\"\u003eActive Pharmaceutical Ingredient:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"7,0,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,1,0,0\"\u003e\u003cb data-path-to-node=\"7,0,1,0,0\" data-index-in-node=\"0\"\u003eProton 20 mg:\u003c\/b\u003e Pantoprazole sodium sesquihydrate equivalent to \u003cb data-path-to-node=\"7,0,1,0,0\" data-index-in-node=\"62\"\u003e20 mg pantoprazole base\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,1,1,0\"\u003e\u003cb data-path-to-node=\"7,0,1,1,0\" data-index-in-node=\"0\"\u003eProton 40 mg:\u003c\/b\u003e Pantoprazole sodium sesquihydrate equivalent to \u003cb data-path-to-node=\"7,0,1,1,0\" data-index-in-node=\"62\"\u003e40 mg pantoprazole base\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,1,0\"\u003e\u003cb data-path-to-node=\"7,1,0\" data-index-in-node=\"0\"\u003eEnteric Protective Coating \u0026amp; Excipients:\u003c\/b\u003e Methacrylic acid-ethyl acrylate copolymer dispersion (gastro-resistant film), triethyl citrate, talc, titanium dioxide, iron oxide yellow, and hypromellose.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"8\"\u003eKey Features \u0026amp; Strength Indications\u003c\/h4\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eProduct Type:\u003c\/b\u003e Oral Delayed-Release \/ Gastro-Resistant Tablets (Prescription \/ Pharmacy PPI)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eManufacturer:\u003c\/b\u003e SPIMACO (Saudi Pharmaceutical Industries \u0026amp; Medical Appliances Corporation)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eIndications by Strength:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"9,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,1,0,0\"\u003e\u003cb data-path-to-node=\"9,2,1,0,0\" data-index-in-node=\"0\"\u003eProton 20 mg:\u003c\/b\u003e Mild\/non-erosive gastroesophageal reflux disease (NERD), long-term maintenance and prevention of relapse in healed reflux esophagitis, and prevention of NSAID-induced gastroduodenal ulcers in patients at risk.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,1,1,0\"\u003e\u003cb data-path-to-node=\"9,2,1,1,0\" data-index-in-node=\"0\"\u003eProton 40 mg:\u003c\/b\u003e Moderate to severe erosive reflux esophagitis, active gastric and duodenal ulcers, eradication of \u003ci data-path-to-node=\"9,2,1,1,0\" data-index-in-node=\"112\"\u003eHelicobacter pylori\u003c\/i\u003e (in triple\/quadruple therapy regimens), and pathological hypersecretory conditions including Zollinger-Ellison syndrome.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,3,0\"\u003ePack size: 28 enteric-coated tablets\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"10\"\u003eHow to Use\u003c\/h4\u003e\n\u003cul data-path-to-node=\"11\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,0,0\"\u003e\u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"0\"\u003eAdministration Rule:\u003c\/b\u003e Swallow tablets whole with water. \u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"55\"\u003eDo not crush, chew, split, or break the tablet\u003c\/b\u003e, as damaging the enteric coating causes acid degradation of pantoprazole in the stomach.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,1,0\"\u003e\u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"0\"\u003eTiming:\u003c\/b\u003e Administer \u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"19\"\u003e30 to 60 minutes before breakfast\u003c\/b\u003e (or before breakfast and dinner when prescribed twice daily), coinciding peak blood concentrations with meal-stimulated proton pump recruitment.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Generic","offers":[{"title":"20 mg","offer_id":52180156383527,"sku":null,"price":3.78,"currency_code":"KWD","in_stock":true},{"title":"40 mg","offer_id":52180156416295,"sku":null,"price":6.17,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0708\/5044\/5607\/files\/Proton_20_mg_28_Tablets.jpg?v=1790421346","url":"https:\/\/thetrustpharmacy.com\/en\/products\/proton-28-tablets","provider":"Trust Pharmacy","version":"1.0","type":"link"}