{"product_id":"picoprep-2-sachet","title":"Picoprep 2 Sachet","description":"\u003cp data-path-to-node=\"5\"\u003ePico-Prep is a systemic oral purgative indicated for bowel evacuation and colon cleansing prior to diagnostic colonoscopy, surgical bowel resections, or radiological abdominal examinations. It combines two pharmacologically distinct and synergistic bowel-cleansing mechanisms: \u003cb data-path-to-node=\"5\" data-index-in-node=\"277\"\u003eSodium Picosulfate\u003c\/b\u003e (a local stimulant laxative) and \u003cb data-path-to-node=\"5\" data-index-in-node=\"329\"\u003eMagnesium Citrate\u003c\/b\u003e (an osmotic laxative formed \u003ci data-path-to-node=\"5\" data-index-in-node=\"375\"\u003ein situ\u003c\/i\u003e when magnesium oxide and citric acid react in aqueous reconstitution). Sodium picosulfate is cleaved by bacterial sulfatases within the colonic lumen to produce bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), directly stimulating peristaltic motility in the colonic wall. Concurrently, magnesium citrate retains high volumes of water within the colonic lumen via osmotic force, diluting fecal contents and inducing rapid mechanical evacuation. It is supplied as a powder for oral solution with an orange flavor, packaged in a box containing \u003cb data-path-to-node=\"5\" data-index-in-node=\"924\"\u003e2 unit-dose sachets\u003c\/b\u003e.\u003c\/p\u003e\n\u003cp data-path-to-node=\"5\"\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"6\"\u003eKey Benefits\u003c\/h4\u003e\n\u003cul data-path-to-node=\"7\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,0,0\"\u003e\u003cb data-path-to-node=\"7,0,0\" data-index-in-node=\"0\"\u003eSynergistic Dual Purgative Action:\u003c\/b\u003e Unites the contact peristaltic stimulation of sodium picosulfate with the high osmotic volume retention of magnesium citrate for reliable colonic clearance.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,1,0\"\u003e\u003cb data-path-to-node=\"7,1,0\" data-index-in-node=\"0\"\u003eLow Ingestion Volume:\u003c\/b\u003e Requires drinking only a small volume (approx. 150 ml) of the reconstituted active medicinal solution per sachet, reducing nausea compared to large-volume polyethylene glycol (PEG) regimens.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,2,0\"\u003e\u003cb data-path-to-node=\"7,2,0\" data-index-in-node=\"0\"\u003eComplete Mucosal Visualization:\u003c\/b\u003e Promotes high diagnostic visibility during endoscopic inspection, facilitating polyp detection and mucosal mucosal mucosal evaluation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,3,0\"\u003e\u003cb data-path-to-node=\"7,3,0\" data-index-in-node=\"0\"\u003eRapid Evacuation Profile:\u003c\/b\u003e Begins producing frequent watery evacuations within 2 to 4 hours following ingestion of the initial reconstituted sachet.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"7,4,0\"\u003e\u003cb data-path-to-node=\"7,4,0\" data-index-in-node=\"0\"\u003ePalatable Formulation:\u003c\/b\u003e Orange flavoring masks active mineral salts, supporting patient adherence during rigorous pre-procedure preparation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"8\"\u003eKey Ingredients (per single sachet)\u003c\/h4\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eSodium Picosulfate (10 mg):\u003c\/b\u003e Prodrug converted by colonic bacteria into the active prokinetic contact laxative BHPM.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eLight Magnesium Oxide (3.5 g):\u003c\/b\u003e Reacts with citric acid in solution to form osmotic magnesium citrate.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eAnhydrous Citric Acid (12 g):\u003c\/b\u003e Reactant for magnesium citrate generation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,3,0\"\u003e\u003cb data-path-to-node=\"9,3,0\" data-index-in-node=\"0\"\u003eExcipients \u0026amp; Flavoring:\u003c\/b\u003e Potassium hydrogen carbonate, sodium saccharin, and natural orange flavor.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4 data-path-to-node=\"10\"\u003eKey Features\u003c\/h4\u003e\n\u003cul data-path-to-node=\"11\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,0,0\"\u003e\u003cb data-path-to-node=\"11,0,0\" data-index-in-node=\"0\"\u003eProduct Type:\u003c\/b\u003e Oral Purgative \/ Bowel Evacuant (Prescription Colonic Cleansing Agent)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,1,0\"\u003e\u003cb data-path-to-node=\"11,1,0\" data-index-in-node=\"0\"\u003eIndications:\u003c\/b\u003e Complete bowel cleansing prior to screening colonoscopy, barium enema examinations, or colorectal surgery\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,2,0\"\u003eLow-volume active suspension with mandatory supplementary clear fluid hydration\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"11,3,0\"\u003ePack size: 2 unit-dose sachets (powder for oral reconstitution)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch4 data-path-to-node=\"12\"\u003eHow to Use\u003c\/h4\u003e\n\u003cul data-path-to-node=\"13\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,0,0\"\u003e\u003cb data-path-to-node=\"13,0,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Dissolve the contents of 1 sachet in a glass of cold water (approx. 150 ml). Stir for 2 to 3 minutes until the powder completely dissolves; the solution may become warm due to the acid-base reaction—allow it to cool before drinking.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,1,0\"\u003e\u003cb data-path-to-node=\"13,1,0\" data-index-in-node=\"0\"\u003eSplit-Dose Regimen (Standard):\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"13,1,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,1,1,0,0\"\u003e\u003cb data-path-to-node=\"13,1,1,0,0\" data-index-in-node=\"0\"\u003eFirst Sachet:\u003c\/b\u003e Ingested the afternoon or evening (e.g., 5:00 PM to 8:00 PM) before the scheduled morning procedure, followed by drinking at least \u003cb data-path-to-node=\"13,1,1,0,0\" data-index-in-node=\"145\"\u003e5 glasses of clear fluids\u003c\/b\u003e (approx. 250 ml each, total 1.25 L) over the next few hours.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,1,1,1,0\"\u003e\u003cb data-path-to-node=\"13,1,1,1,0\" data-index-in-node=\"0\"\u003eSecond Sachet:\u003c\/b\u003e Ingested the following morning approximately \u003cb data-path-to-node=\"13,1,1,1,0\" data-index-in-node=\"60\"\u003e4 to 6 hours prior to the procedure\u003c\/b\u003e (or the preceding late evening depending on hospital protocol), followed by drinking at least \u003cb data-path-to-node=\"13,1,1,1,0\" data-index-in-node=\"190\"\u003e3 glasses of clear fluids\u003c\/b\u003e (approx. 750 ml) up until 2 hours before the examination.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,2,0\"\u003e\u003cb data-path-to-node=\"13,2,0\" data-index-in-node=\"0\"\u003eMandatory Hydration Protocol:\u003c\/b\u003e Consuming the required clear liquids (water, clear broth, diluted apple juice, electrolyte solutions) is essential to prevent dehydration and hypovolemia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"13,3,0\"\u003eContraindicated in cases of congestive heart failure, severe renal insufficiency, gastrointestinal obstruction, ileus, toxic megacolon, gastric retention, or active bowel perforation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Generic","offers":[{"title":"Default Title","offer_id":52214265315623,"sku":null,"price":2.17,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0708\/5044\/5607\/files\/Picoprep_2_Sachet.jpg?v=1790966366","url":"https:\/\/thetrustpharmacy.com\/en\/products\/picoprep-2-sachet","provider":"Trust Pharmacy","version":"1.0","type":"link"}