Omcet 10 mg 28 tablets

Omcet 10 mg is an oral second-generation antihistamine formulated for the rapid and long-lasting relief of systemic and cutaneous allergic manifestations. Powered by Cetirizine Dihydrochloride (10 mg), a selective peripheral histamine $H_1$-receptor antagonist and active carboxylated metabolite of hydroxyzine, it inhibits histamine-mediated early-phase vascular exudation, capillary permeability, and sensory nerve stimulation, while suppressing the late-phase recruitment of eosinophils into cutaneous and mucosal tissues. With minimal blood-brain barrier penetration compared to first-generation agents, it delivers continuous 24-hour symptom control with a low incidence of central sedation, packaged in a box containing 28 film-coated tablets (2 blister strips of 14 tablets).

Key Benefits

• Rapid Onset & 24-Hour Coverage: Achieves clinical onset within 20 to 60 minutes and maintains sustained peripheral receptor blockade for a full 24 hours on a single daily dose.

• Dual-Phase Allergic Control: Inhibits early-phase allergic mediator release (itching, sneezing, watery rhinorrhea) and attenuates late-phase inflammatory cell infiltration (eosinophil migration).

• Minimal Central Nervous System Sedation: Low lipophilicity restricts passage across the blood-brain barrier, offering a favorable vigilance profile over first-generation antihistamines.

• Broad-Spectrum Anti-Allergic Utility: Highly effective across upper respiratory tract allergies (allergic rhinitis) as well as dermatological conditions (chronic idiopathic urticaria).

• Low Hepatic Metabolic Burden: Eliminated primarily via renal excretion in unchanged form, minimizing CYP450-mediated drug-drug interactions.

Key Ingredients (per tablet)

• Cetirizine Dihydrochloride (10 mg): Selective, high-affinity competitive antagonist of peripheral histamine $H_1$ receptors.

• Pharmaceutical Excipients: Lactose monohydrate, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, hypromellose (HPMC), titanium dioxide, and macrogol/PEG (film-coating polymer).

Key Features

• Product Type: Oral Antihistamine Film-Coated Tablet

• Indications: Seasonal allergic rhinitis (hay fever), perennial allergic rhinitis, allergic conjunctivitis (ocular pruritus and lacrimation), and chronic idiopathic urticaria (wheal-and-flare reactions)

• Convenient once-daily dosing regimen

• Pack size: 28 film-coated tablets (2 strips × 14 tablets)

How to Use

• Administration: Swallow whole with a glass of water, with or without food.

• Dosage for Adults and Adolescents 12 years: 1 tablet (10 mg) once daily, preferably in the evening.

• Dosage for Children (6 to 12 years): 5 mg (half a tablet) twice daily, or 10 mg (one tablet) once daily.