Gyno Mikozal 400 mg 3 ov

Gyno-Mikozal 400 mg Vaginal Ovules is a targeted gynecological antifungal medication indicated for the short-course treatment of vulvovaginal candidiasis (vaginal yeast infections) and associated superinfections caused by Gram-positive bacteria. Powered by Miconazole Nitrate (400 mg), a synthetic imidazole derivative, it inhibits the fungal cytochrome P450 enzyme. This action halts the conversion of lanosterol into ergosterol, disrupting fungal membrane integrity, increasing permeability, and precipitating fungal cell lysis. Formulated in a bio-adhesive, smooth-melting suppository base, it delivers high local tissue concentrations with negligible systemic absorption, packaged in a blister strip containing 3 vaginal ovules.

Key Benefits

• High Clinical Cure Rate: Delivers high eradication rates against Candida albicans and other susceptible non-albicans fungal species.

• Rapid Symptom Relief: Promptly relieves intense vaginal pruritus, burning sensations, vulvar edema, and abnormal curd-like discharge within the initial days of treatment.

• Short 3-Day Course: High-strength (400 mg) dosing allows an intensive short-duration therapy, maximizing patient compliance compared to 7- or 14-day low-dose regimens.

• Antibacterial Coverage: Exhibits secondary bacteriostatic activity against Gram-positive cocci and bacilli, managing mixed fungal-bacterial vaginal superinfections.

• Minimal Systemic Bioavailability: Acts locally with low systemic absorption, minimizing systemic interactions and systemic side effects.

Key Ingredients (per ovule)

• Miconazole Nitrate (400 mg): Broad-spectrum imidazole antifungal active agent.

• Suppository Base: Hard fat / semi-synthetic glycerides (lipophilic base engineered to melt uniformly at human body temperature).

Key Features

• Product Type: Intravaginal Ovules / Suppositories (Gynecological Anti-Infective)

• Indications: Acute and recurrent vulvovaginal candidiasis, mycotic vaginitis, and secondary Gram-positive vaginal infections

• Short, intensive 3-day treatment duration

• Pack size: Blister pack of 3 vaginal ovules

How to Use

• Wash hands thoroughly before opening and handling the ovule.

• Insert 1 ovule deeply into the vagina once daily at bedtime for 3 consecutive nights.

• Best inserted while lying on your back with knees bent up toward the chest.

• Use panty liners to protect clothing from melting ovule base discharge; do not use tampons during treatment.

• Avoid sexual intercourse during the active treatment period; the lipophilic suppository base can compromise and rupture latex condoms and diaphragms.

• Continue and complete the full 3-day course even if menstruation commences during treatment.