Euthyrox 25 Microgram 100 tab

Euthyrox 25 mcg is an oral endocrine medication containing Levothyroxine Sodium (25 mcg / 0.025 mg), a synthetic levorotatory isomer of thyroxine (T4). Identical in physiological structure and receptor dynamics to endogenous thyroid hormone secreted by the human thyroid gland, it undergoes peripheral 5'-deiodination in non-thyroidal tissues (primarily the liver and kidneys) to yield the biologically potent metabolite triiodothyronine (T3). Active T3 enters cell nuclei to bind thyroid hormone receptors, regulating basal metabolic rate, protein synthesis, lipid and carbohydrate turnover, thermogenesis, and cardiovascular responsiveness. The 25 mcg low-dose strength is primarily utilized as an initial starter dose, a gradual titration increment, or a maintenance dose for fragile populations, packaged in a box containing 100 scored tablets (4 blister strips of 25 tablets).

Key Benefits

• Physiological Bio-Equivalence: Identical molecular architecture and metabolic fate to endogenous thyroxine (T4), restoring optimal systemic endocrine balance.

• Precise Dose Calibration & Titration: The 25 mcg increment permits stepwise upward titration without precipitating acute cardiac strain or thyrotoxic arrhythmias.

• Safer Induction for Fragile Cohorts: Recommended starting strength for elderly patients, individuals with underlying coronary artery disease, or severe long-standing myxedema.

• Metabolic Rate Normalization: Alleviates hallmark symptoms of hypothyroidism, including chronic lethargy, cold intolerance, weight gain, constipation, dry skin, and bradycardia.

• Long Biological Half-Life: Displays a stable elimination half-life of 6 to 7 days in euthyroid individuals, ensuring smooth steady-state plasma concentrations with once-daily dosing.

Key Ingredients (per tablet)

• Levothyroxine Sodium (25 mcg / 0.025 mg): Synthetic crystalline sodium salt of levo-thyroxine.

• Tablet Core Excipients: Mannitol, corn starch, gelatin, croscarmellose sodium, citric acid anhydrous, and magnesium stearate.

Key Features

• Product Type: Oral Synthetic Thyroid Hormone (Narrow Therapeutic Index Medication)

• Indications: Replacement therapy in primary, secondary, and tertiary hypothyroidism; step-up titration in subclinical hypothyroidism; suppression therapy for benign euthyroid goiter; adjunct to radioiodine or surgical thyroidectomy in thyroid carcinoma

• Scored tablets allowing functional halving if micro-adjustments are required

• Pack size: 100 tablets (4 blister strips × 25 tablets)

How to Use

• Take once daily in the morning on an empty stomach, at least 30 to 60 minutes before breakfast, swallowed whole with a full glass of water.

• Do not take with coffee, tea, milk, or soy products, as they substantially reduce gastrointestinal absorption.

• Drug Interaction Window: Separate by at least 4 hours from calcium carbonate, iron supplements (e.g., Ferose), multivalent antacids (Al/Mg hydroxides like Moxal Plus), bile acid sequestrants, and sucralfate, which bind levothyroxine in the intestinal lumen.

• Regular serum TSH and Free T4 monitoring is required (typically evaluated 6 to 8 weeks after dose initiation or adjustment) to titrate to the target therapeutic window.